Nanomark Therapeutics Wins 2010 NVC!

10 04 2010

Congratulations to Nanomark Therapeutics, the 2010 New Venture Championship Champions!

We’re one step closer to curing cancer as NanoMark Therapuetics from Louisville University won the 2010 New Venture Championship, a business plan competition held by the Charles H. Lundquist Center for Entrepreneurship of the University of Oregon, and was awarded $25,000.

NanoMark Therapeutics’ business plan introduces a product, AUra, that enhances the treatment of ovarian cancer by minimizing the negative side effects to healthy cells and limiting dosage requirements.

“It’s the top of the peak for us right now,” NanoMark Therapeutics Chief Medical Officer Dr. Gary Degen said. “The competition here was so strong and to walk out on top is beyond our wildest dreams.”

The second place team Mosaic Genetics LLC from the University of Oregon earned $10,000.

Winning the New Venture Championship means entry in the 2010 Moot Corp Competition, a business-plan contest held at The University of Texas at Austin. Because NanoMark Therapeutics already has earned a spot in the competition, Mosaic Genetics has earned an invitation to the competition.

Third place finisher, Green Valley Solar from the University of Arkansas, received $2,500, and two runner-up teams, Microfluidic of Purdue University and Bombyx Technologies of Cornell University each received $2,000.

NanoMark Therpeutics from Louisville University also won $1,000 for first place in the Tektronix Elevator Pitch competition and Cortical Concepts from Johns Hopkins University was awarded $1,000 for first place in the Tektronix Trade Show competition.

Green Valley Solar from the University of Arkansas was awarded $1,000 for having the best-written business plan.

In the Oregon Entrepreneurs Network Lightning Round, each of the following winning teams earned $1,250: A2K Technologies from University of Manitoba, Thermal Conservation from University of Illinois at Chicago, Mielixir from Sasin, SafeSnip from Tulane University, and R2EV from Boise State University won $1,250. All other teams competing were awarded $500 as runners-up.

For more information on the New Venture Championship, please go to http://www.oregonnvc.com.





Nanomark Therapeutics – Finalist Presentation

10 04 2010

In 2010, it is predicted that cancer will become the most deadly disease worldwide. NanoMark Therapeutics decided to tackle the challenge of fighting cancer.

Dr. Sham Kakar, the founder of NanoMark Therapeutics, has created a groundbreaking new system of delivering drugs directly to the cancerous cells of the body while sparing healthy cells.

Louisville's five-person team graces the NVC stage

The system reduces the needed dosage by 200% and reduced total treatments from 24 to four. This reduction in dosage also decreases the risk of side effects. Each individual consumer dosage costs more than traditional cancer treatments, but with the reduced number of treatments the increase in cost to the patient is minimal.

The team is currently conducting their first round of animal testing and expects to begin clinical trials on humans in 2011. The team stressed that all research and development has been performed with grants from their school and organizations, and there has been no dilution of potential stock options for investors.





Mosaic Genetics LLC – Final Presentation

10 04 2010

One in three women and one in two men will develop cancer in their lifetime. Nearly everyone knows or will know someone with cancer. Mosaic Genetics LLC is revolutionizing cancer research, one mouse at a time. The trio from the University of Oregon is bringing to market a new drug discovery tool, which will allow scientists to unlock the secrets of cancer at the cellular level. Catering to scientists’ research, Mosaic Genetics LLC crafted the LumiMouse – a new model, single cell view that enables cancer to develop in a natural location.

The University of Oregon team flashes their "O" at the NVC

The LumiMouse provides a systematic view of what is going on inside the body, unlike the current mouse model, “xenograft.” Green illumination represents cancer and red illumination signifies healthy cells.  This enables scientists to see what is happening in every individual cancer cell and every individual healthy cell. The LumiMouse also develops cancer for every test.

Providing detailed examples about their competitors, Mosaic Genetics LLC has developed their marketing strategy around academic validation with targeted researchers and commercial customers. They expect an 18-24 month product development stage and currently have a patent, filed in August 2009, covering targeted cancer growth and the dual color illumination.

With $100,000 current funds from family, friends and founders, Mosaic Genetics LLC predicts two phases of outside investment totaling $4 million. Within five years, the LumiMouse will come in five models for cancer research: breast, brain, prostate, colon and lung.

Teammates Elizabeth Holsapple, Nick Boehm and Yonatan Schultz equally answered the finalist judges’ Q&A session promptly and efficiently and stood proud representing their new cancer research tool in the form of a mouse. Mosaic Genetics LLC predicts three hurdles, including licensing the red and green fluorescents, use of mice because LumiMouse cannot breed, and personnel.





Green Valley Solar Presents in the Final Round

10 04 2010

Green Valley Solar from the University of Arkansas plans to better the world by improving the solar generated electricity. Addressing high manufacturing in the solar market come from wasted materials, the team introduced a solution to this issue with promising “solar has never been so green.”

Green Valley Solar, represented by senior scientist, Seth Shumate, and vice president of communications, Stephan Ritterbush, has worked with their team to develop a large-grain polysilicon cell solution generating grains 90 times larger, thus separating boundaries and reducing silicon costs. There are currently two types of crystalline silicon used in the industry. Green Valley Solar is striving to by-pass the waste and inefficiencies that each of these production processes can cause.

The two representatives from the University of Arkansas grace the stage

Materials used by competing products have proven to be highly toxic. Shumate and Ritterbush spoke to the idea that the European Union is in the process of working against such products for this exact reason. Not only has Green Valley Solar solidified an experienced management team to confront this problem, but the team also capitalizes on the low toxicity of their cell structure.

Green Valley Solar’s technological solution has been protected by five patents, of which two are related to grain size and three are related to medal induced crystallization. With these patents, Shumate and Ritterbush ensured the judging panel that their technology was secure and prepared to move forward.

And, moving forward they are.

Green Valley Solar has already earned the compliance of the Department of Energy, established a relationship with Sanyo to produce samples and scheduled a meeting with Sharp. In the coming months, Green Valley Solar plans to engage in heat sample testing and can take their experiences at the NVC in the continuation of their venture.





Microfluidic Innovations LLC – Finalist Presentation

10 04 2010

Worldwide pandemics such as H1N1 cause death and destruction. However, these are preventable. Microfluidics Innovations LLC is marketing a better opportunity for scientists to find a cure.

The venture, traveling from Purdue University, focuses on minute amounts of liquid being processed in order to do research in the fields of biochemistry, genomics, biotechnology and DNA analysis. Much of this research is accomplished by using lab-on-a-chip technology, which utilizes small glass chips with grooves to channel and alter liquids.

Microfluidic Innovations LLC has created a revolutionary new form of lab-on-a-chip that is infinitely programmable to match the desires of research labs and pharmaceutical companies. A lab currently must go through the time-intensive process of designing, fabricating, and testing chips, and often would have to return to each step multiple times in order to get what they needed.

With the new technology that team members Leonard Kim and Samir Sahoo propose, labs will only have

Microfluidic Innovations LLC poses for the camera

to create an idea, write a simple program or click a few buttons, and produce a working chip that can be used directly in experiments. Instead of a production timeline of 3-6 months, the whole process can be completed in 3-6 hours.

The team already has an international patent on their technology, with two more patents pending, and an exclusive license with Purdue University to use the technology.

Microfluidic Innovations, LLC hopes to tap into a $56 billion dollar market that is expected to grow annually by 13%. They plan on offering their new chips to researchers who are required to mention the product, and parlay that free advertising into sales agreements with both academic organizations and companies that use the chips.





Bombyx Technologies – Final Round

10 04 2010

Over five million eye injuries in America each year, many of which result with a slow and low recovery rate that often takes months and can even result in blindness. Bombyx Technologies, which includes team members Benjamin Rollins and Brian Lawrence (a co-inventor), has created the first regenerative bandage for the eye that absorbs, dissolves and rapidly heals wounds within only a few weeks.

Cornell University presented with class and poise in the finals

Rollins and Lawrence were well composed while presenting their regenerative eyesight bandage. The team currently has more than $1 million in funds distributed from Cornell University. Bombyx Technologies’ bandage not only protects, it also replaces and regenerates over a two-week span. Similar to a contact lens, their product is comprised of a special substance that adheres to the eye to repair soft tissue; then it rapidly dissolves. It’s that simple! Bombyx absorbs to your eye while healing, and dissolves to shield and protect.

Lawrence gave an example of a friend of his who had recently fell asleep with her contacts in – a common occurrence among contact lens wearers. The next morning her contacts had dried up so extensively that she tore off part of her cornea trying to remove it. Constructive surgery is expensive, painful and requires a long recovery. Lawrence indicated that it’s likely that if his friend had been able to use Bombyx Technologies’ bandage, she would have had full recovery within two weeks.

With the “potential to revolutionize,” the bandage has a remarkable one-year shelf life.

Bombyx Technologies has a market strategy including strong relationships with key opinion leaders, PRK laser surgeons, ophthalmologists and ER physicians. Although they already have a prototype, Rollins and Lawrence need to begin clinical trials, which will start in the Dominican Republic. By year five of their product launch, they project the bandage will be in 900 of 1,200 desired locations





Schedule of Finalists

10 04 2010

Today’s finalists are now underway.

Here is the schedule of presenters:

9:00 a.m. Bombyx Technologies (Cornell University)
10:00 a.m. Microfluidic Innovations LLC (Purdue University)
11:00 a.m. Green Valley Solar (University of Arkansas)
12:30 p.m. Mosaic Genetics (University of Oregon)
1:30 p.m. NanoMark Therapeutics (University of Louisville)

Stay tuned for updates on the day. For more information, visit our Twitter page or http://www.oregonnvc.com





Finalists Announced at NVC

9 04 2010

Five teams have been selected to compete in Saturday’s final round at the 19th annual New Venture Championship. Bombyx Technologies (Cornell University), Microfluidic Innovations LLC (Purdue University), Green Valley Solar (University of Arkansas), Mosaic Genetics (University of Oregon), and NanoMark Therapeutics (University of Louisville) will have the opportunity to compete for the $25,000 grand prize.

Bombyx Technolgies has developed a bandage that enhances the healing process of the eye. Just like a contact lens, the product is comprised of silk proteins that remarkably adhere to the eye to repair soft tissue and rapidly dissolve. The bandage was developed to heal chronic eye wounds and reduce chances of vision loss by emphasizing the body’s natural healing process.

Microfluidic Innovations LLC has delivered the first ever general-purpose, programmable microfluidic lab-on-a-chip that can be reprogrammed to serve the purposes of academic research labs as well as major companies. Their groundbreaking technology shortens the time needed by labs to run experiments from 3-6 months to 3-6 hours.

Green Valley Solar will find itself presenting tomorrow at 11:00 a.m. in the Final Round

Green Valley Solar is licensing their technology for solar panels that are more efficient and over 26% cheaper than the panels currently available. The team hopes to market their products for large companies, and already in talks with Sanyo.

Mosaic Genetics LLC is bringing to market a new drug discovery tool in the form of a genetically engineered mouse, which will allow scientists to unlock the secrets of cancer at the cellular level. The team crafted the LumiMouse – a new model with a single cell view that enables cancer to develop in a natural location.

NanoMark Therapeutics, the winner of the NVC’s Elevator Pitch Competition, has presented AUra – a uniquely targeted cancer drug with low toxicity, specialized hormone surface and ability to kill cancerous cells while minimizing the death of healthy cells. Compared to other leading drugs in animal testing, The Federal Drug Administration approved product kills cancerous cells at a much higher rate than current competitors at a fraction of the cost.

The New Venture Championship will provide live commentary and announcement during Saturday’s final round via the social networking service Twitter found under the profile OregonNVC, as well as through the NVC blog, http://www.oregonnvc.wordpress.com. For more information, please visit http://www.oregonnvc.com.





Semifinal Presentations – Impressive as Usual

9 04 2010

When New Venture Championship Managing Director Terry Sebastian spoke to the impressiveness of the competitors last night, he placed high expectations amongst the twenty teams presenting today.

The teams did not disappoint.

Each team presented with confidence, poise, and professionalism.

We were able to sit in on 16 of the 20 semifinal presentations. Here is a summary:

R2EV – Boise State

R2EV consists of Alex Livingston, Thomas Schoeck and Marcel Wermeckes

R2EV of Boise State was a part of the first track that presented at 8:45 this morning. The team began by pitching their update to the traditionally expensive Uninterrupted Power Supplies (UPS) systems that are needed to supply companies with backup electricity when the power goes out.

The trio employs their patent-pending lithium technology to produce a battery with a lifespan of three times the battery life and four times the power available as the current product. R2EV has pilot programs already set up in a large grocery chain, but have come to the NVC to perfect their business plan that will allow them to access a 60 billion dollar market. They have plans to partner with the U.S. Government’s green energy initiative to cut costs and help the planet.

Ordoro – University of Texas at Austin

The Ordoro team consits of Jagath Narayan, Sangram Kadam and Naruby Schlenker

The Ordoro team has been bootstrapping their company to simplify the process that over 500,000 small online businesses go through to manage their inventory and sales. The University of Texas at Austin team sets out to replace the clunky and incomplete order management systems available. The trio has made progress by creating a simple, web-based inventory organization program to simplify sales and make business owner’s lives easier.

The team changed the pace of the pitch by throwing questions at Judge Steve Cord to make their presentation more clear and understandable. After Ordoro’s conclusion, the team said, “The variety of the competition is great.” They also credited the judges with giving them “great feedback.”

Microfluidic Innovations LLC – Purdue University

The Microfluidic team poses on the NVC stage

Microfluidic Innovations LLC presented their patent-pending proprietary lab-on-a-chip that can be reprogrammed to serve the purposes of academic research labs as well as major companies. Their groundbreaking technology shortens the time needed by labs to run experiments from 3-6 months to 3-6 hours. All of this is done in a cheap and affordable manner.

The team said that although they had to simplify their pitch to make the science-heavy process relevant to the judges, “the feedback was still very helpful.”

CyrusPath – San Diego State University

Craig Stern entertains the crowd during the Elevator Pitch conversation

CyrusPath bills itself as “the new wave of language acquisition.” The startup backs up its claim with a novel implementation of language translation into text messaging.

Stern proposes that CyrusPath can help the estimated one billion people currently attempting to learn a new language. This equates to about 80 billion dollars in sales! Stern hopes to break into the market with innovative techniques such as text-to-speech and colloquialism translation.

A2K Technologies – University of Manitoba

University of Manitoba members Andrea Legary, Anocha Jivanuwong and Katherine O'Rourke pose on the NVC stage

A2K Technologies, traveling from the University of Manitoba in Canada, introduced its product, ColoSpec, to its judges. ColoSpec is an alternative to the standard colonoscopy. This simple-to-use product can help lower the rate of colon cancer- one of the most preventable types of cancer. With a 92% accuracy rate, ColoSpec looks to help increase the rate of adults ages 50 and older that currently get tested annually.

Nalu Solar – University of Michigan

University of Michigan teammates Jennifer McLaughlin, Prashanth Prasad and Imogen Taylor on the NVC stage

Nalu Solar shined in their 15-minute presentation about their innovative software that allows big businesses and do-it-yourself types to build building-specific solar panels while guiding them through every step from visualization to creation. The University of Michigan-based team’s pitch focused on the gap that would be filled by the ease and affordability of their software that would bring back an estimated 150% return on investment.

“More than jumping on the DIY bandwagon, it’s about filling a market need,” Douglas Hutchings of Nalu Solar said.

Green Valley Solar – University of Arkansas

Green Valley Solar on the NVC stage

Green Valley Solar, with a catchphrase of “Solar has never been so green.” The team uses a patented groundbreaking technology to reduce the price of silicon-based photovoltaic devices.

Green Valley Solar has created 26% cheaper solar panels that are more efficient than the panels currently available. The team, traveling from the University of Arkansas, hopes to market their products for large companies, and has already entered into a deal with Sanyo.

Marere Pure Water – Brigham Young University

Marere Pure Water from Brigham Young University

Marere Pure Water has created a business around helping water-deprived East Africans. The participants, hailing from Brigham Young University, plan to implement their new ultra-cheap, easily accessible, biodegradable and clean 18oz bags of drinking water in Kenya, where dirty water leads to 50-70% of disease.

Marere Pure Water argues that bags of water are vital for the health of Kenya and yield a 74% profit margin. The team has already made major plans for implementation, and is partnered with the Ambassador of Kenya. One judge was surprised at the completeness of the plan, saying, “I walked in here very skeptical, and I’m walking out of here very impressed.”

NanoShield – Georgia Institute of Technology

The NanoShield team poses for a team picture

NanoShield invented a safe, effective and low-cost proprietary coating technology that doubles the useful life of central venous catheters (CVC), thereby reducing the need for surgical interventions and the thousands of dollars of costs they incur.

With great eye contact and voice projection, team members Nikhil Patel, Andy Sanders and Jake Sisley clearly identified that 75% of CVC become blocked from health hazards within three months. Providing both remedial and preventative solutions, NanoShield is of high value to an intravenous market and provides a $3 to $4 billion saving each year in the U.S.

The judges shot out tough questions for NanoShield, but each member answered with educated insight.  NanoShield has no current formal agreements but foresees obtaining their license within the next eight months.

When asked about their presentation, NanoShield teammates and their adviser felt very prepared for the Q&A session in part because of yesterday’s practice round. Adviser Margi Berbari was excited with her team and says the group did “phenomenally!”

Mosaic Genetics – University of Oregon

Mosaic Genetics presents during their semifinal round

Mosaic Genetics LLC is revolutionizing cancer research, one mouse at a time. The trio from the University of Oregon is bringing to market a new drug discovery tool, which will allow scientists to unlock the secrets of cancer at the cellular level. Catering to scientists’ research, Mosaic Genetics LLC crafted the LumiMouse – a new model, single cell view that enables cancer to develop in a natural location.

Providing detailed examples about their competitors, Mosaic Genetics LLC has developed their marketing strategy around academic validation with targeted researchers and commercial customers. Teammates Elizabeth Holsapple, Nick Boehm and Yonatan Schultz equally answered the judges’ Q&A session promptly and efficiently.

SafeSnip – Tulane University

SafeSnip team members pose on the NVC stage

Tulane University students William Kethman, Stephanie Roberts and Alex Chan presented their invention, SafeSnip, and wowed judges with their product and devotion.  SafeSnip is a disposable, plastic medical device that improves birthrates by revolutionizing the way doctors cut umbilical cords.

SafeSnip, a one-time use device, was developed with a plastic blade based on sheer force that prevents disease growth on the umbilical cord.  With an untouched market space, SafeSnip will target both developing and developed countries, focusing primarily in Bangladesh, where there is a high population, high rate of infant mortality and majority of births globally.

The team’s manufacturing strategy focuses on a plastic injection mold, which is their primary causation for funding.  Luckily, the product is very cheap to produce, allowing the potential to help many in the future.

Thermal Conservation Technologies – University of Illinois at Chicago

The Thermal Conservation Technologies team consists of Laura Kilbanow, Jacob Kist and James Parks

Thermal Conservation Technologies wants to help truck drivers limit their negatives. The start up helps limit fuel usage, allows for more product space, and even qualifies for a tax credit. The early-stage company from the University of Illinois-Chicago is committed to energy preservation and sustainability through the utilization of high-performance vacuum insulation.

The first application is Klimate Kontrol, which reduces operating costs by up to 50% and increases carrying by up to 27% due to thinner insulation. Team members Laura Klibanow, Jacob Kist and James Parks were on point during their presentation. With an impressive presentation, poise and a slide show that affectively aided rather than guided their presentation, Thermal Conservation Technologies was well prepared and enthusiastic about this trucking dilemma.

Klimate Kontrol will vastly contribute to decreasing the national use of diesel fuel and address environmental fines, food quality awareness and increasing raw materials.  With trusted and expert partnerships, Thermal Conservation Technologies project operators will see ROI by the end of quarter three and a 9X ROI for early investors!

Beyond Lucid – Carnegie Mellon University

Carnegie Mellon holds up their MediView banner on the NVC stage

46.4% of patient data is lost during the hand off into the emergency room. Beyond Lucid of Carnegie Mellon University plans to close this gap between ambulances and hospitals by introducing MediView, a healthcare IT system that securely, remotely, and wirelessly transmits real-time vital patient data to doctors inside a hospital emergency room. All of this occurs while patients are still in the ambulance en route to the hospital.

MediView collects vital data by using sensors and materials that EMT workers are already familiar with. With little change and much to gain, Beyond Lucid is looking to save lives by enhancing effectiveness of ambulance travel.

NanoMark Therapeutics – Louisville University

The NanoMark Therapeutics team consists of Sham Kakar, Gary Degen, Cohin Kakar, Dave Noack and Viji Sundar

In 2009, more than 15 thousand women died from ovarian cancer and more than 21 thousand new cases were diagnosed. Though explanations for cancer remain a mystery, scientific innovators from the University of Louisville have developed a treatment alternative to the side effects caused by today’s other leading drugs.

NanoMark Therapeutics
presented AUra – a uniquely targeted cancer drug with low toxicity, specialized hormone surface and ability to kill cancerous cells while minimizing the death of healthy cells. Compared to other leading drugs in animal testing, AUra’s competitors killed less than 70% of cancerous cells, whereas AUra was able to kill 95%, and at a fraction of the cost. Chemotherapy drugs tend to cost as much as $100,000, but AUra treatment would cost almost half that, at around $45,000. The future of AUra looks bright for the NanoMark Therapeutics team and ultimately, the human race.

Cortical Concepts – Johns Hopkins University

The Johns Hopkins team, Cortical Concepts, takes the NVC stage

Osteoporosis and low bone mass debilitate the lives of almost 52 million U.S. women and men aged 50 and older. It’s being estimated that by the year 2020 this figure will climb to over 61 million.

In a spinal fusion, titanium screws and rods are placed into the vertebra, which decompress the nerves around the area and destabilize the spine. However, placing these screws into the vertebra of someone with osteoporosis can be compared to “putting a screw into drywall”, says Nicolas Martinez, which is why these screws have difficulty stabilizing and tendency to toggle out.

A team of engineers from John Hopkins University has patented a solution to increasing the fixation strength of the screws in this procedure for those with the disease: the Cortical Anchor. This team calls themselves Cortical Concepts. Already in communication with the FDA Director of Spine, the Cortical Anchor has already sparked excitement amongst the medical community and made a lasting impression on the New Venture Championship.

Bombyx Technologies – Cornell University

The lone Cornell University representative, Ben Rollins, takes the stage.

Benjamin Rollins, the CEO of Bombyx Technologies, conveyed an earnest passion for eye care technology by beginning his presentation with the story of a friend who slept in contact lenses and torn her corneas. However, his friend’s compelling trauma is not uncommon; Corneal injuries like this blind nearly 2 million people each year, and have led Rollins and his partner Brian Lawrence to pioneer a preventive solution.

Inserted just like a contact lens, their healing bandage is comprised of silk proteins that remarkably adhere to the eye to repair soft tissue and rapidly dissolve. The bandage was developed to heal chronic eye wounds and reduce chances of vision loss by emphasizing the body’s natural healing process. In contrast to a standard eye procedure, which can cost as much as $5.1 million, physicians would be able to sell this product for as low as $40. Bombyx Technology, traveling from Cornell University, has come a long way since its founding in 2009, and it would seem from their participation in the New Venture Championship this year that the eye care industry has a lot more to look forward to.





The Semifinals

9 04 2010

The Start-Up round is over and now it’s time to get to business.

All 20 teams will begin the day by formally presenting their venture plan in the Semifinals. Four esteemed judges will decide who moves to the Finals and who will compete in the Lightning Round.

All 20 teams have been placed into five tracks. The best presentation in each track earns the opportunity to participate in to participate in the Final Round, and have a chance to win the $25,000 top prize.

The breakdown of the five tracks is as follows:

Track 1
Aeos Biomedical (University of British Columbia)
Cortical Concepts (Johns Hopkins University)
NanoMark Therapeutics (University of Louisville)
Mielixir (Sasin)

Track 2
NanoShield (Georgia Institute of Technology)
Mosaic Genetics (University of Oregon)
SafeSnip (Tulane University)
Marere Pure Water (Brigham Young University)

Track 3
Beyond Lucid (Carnegie Mellon University)
A2K Technologies (University of Manitoba)
Mediscan Asia (Thammasat University)
Bombyx Technologies (University of Illinois at Chicago)

Track 4
Alfuel Biotech (HKUST)
Nalu Solar Software (University of Michigan)
Green Valley Solar (University of Arkansas)
Thermal Conservation (University of Illinois at Chicago)

Track 5
R2EV (Boise State University)
Ordoro (University of Texas at Austin)
Microfluidic (Purdue University)
CyrusPath (San Diego State)